Our Health Library information does not replace the advice of a doctor. Please be advised that this information is made available to assist our patients to learn more about their health. Our providers may not see and/or treat all topics found herein.

hyoscyamine and phenyltoloxamine

Pronunciation: HYE oh SYE a meen and FEEN il toe LOX a meen

Brand: Digex NF

What is the most important information I should know about hyoscyamine and phenyltoloxamine?

You should not use this medicine if you have severe ulcerative colitis, or if you are unable to urinate.

Before you take hyoscyamine and phenyltoloxamine, tell your doctor if you have glaucoma, asthma, heart disease, high blood pressure, coronary artery disease, or a thyroid disorder.

What is hyoscyamine and phenyltoloxamine?

Hyoscyamine and phenyltoloxamine is a combination medicine that is used to treat indigestion (upset stomach, gas, bloating), and to reduce stomach acid.

Hyoscyamine and phenyltoloxamine may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking hyoscyamine and phenyltoloxamine?

You should not use this medicine if you are allergic to hyoscyamine or phenyltoloxamine, or if:

  • you have severe ulcerative colitis; or
  • you are unable to urinate.

You may not be able to take this medicine if you have untreated or uncontrolled diseases such as glaucoma, asthma, heart disease, high blood pressure, coronary artery disease, or a thyroid disorder.

Tell your doctor if you have or have had:

  • a bladder obstruction or other urination problems;
  • an enlarged prostate;
  • ulcerative colitis;
  • glaucoma;
  • myasthenia gravis;
  • liver or kidney disease;
  • heart problems; or
  • breathing problems.

Tell your doctor if you are pregnant or breastfeeding.

Do not give this medicine to a child without medical advice.

How should I take hyoscyamine and phenyltoloxamine?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Take with food.

If you break or open a hyoscyamine and phenyltoloxamine capsule, avoid inhaling the powder medicine inside the capsule.

Store at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Take your dose as soon as you can, but only if you are getting ready to eat a meal. If you skip a meal, skip the missed dose and wait until your next meal.

Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking hyoscyamine and phenyltoloxamine?

Avoid taking this medicine at the same time you take an antacid. Antacids can make it harder for your body to absorb hyoscyamine and phenyltoloxamine. You may take the antacid after you have taken hyoscyamine and phenyltoloxamine and eaten a meal.

Drinking alcohol with this medicine can cause side effects.

This medicine may cause blurred vision and may impair your reactions. Avoid driving or hazardous activity until you know how this medicine will affect you.

Avoid becoming overheated or dehydrated during exercise and in hot weather. This medicine can decrease sweating and you may be more prone to heat stroke.

What are the possible side effects of hyoscyamine and phenyltoloxamine?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using hyoscyamine and phenyltoloxamine and call your doctor at once if you have:

  • pounding heartbeats or fluttering in your chest;
  • severe stomach cramps or constipation;
  • little or no urination;
  • confusion, memory problems, slurred speech;
  • diarrhea; or
  • problems with balance or muscle movement.

Side effects such as dry mouth, constipation, and confusion may be more likely in older adults.

Common side effects may include:

  • dizziness, drowsiness;
  • constipation;
  • decreased sweating, decreased urination;
  • dry mouth;
  • blurred vision; or
  • impotence, loss of interest in sex, or trouble having an orgasm.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect hyoscyamine and phenyltoloxamine?

Using hyoscyamine and phenyltoloxamine with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

Tell your doctor about all your other medicines, especially:

  • medicine to treat depression, anxiety, mood disorders, or mental illness;
  • cold or allergy medicine (Benadryl and others);
  • medicine to treat Parkinson's disease;
  • medicine to treat stomach problems, motion sickness, or irritable bowel syndrome;
  • medicine to treat overactive bladder; or
  • bronchodilator asthma medication.

This list is not complete. Other drugs may affect hyoscyamine and phenyltoloxamine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Your pharmacist can provide more information about hyoscyamine and phenyltoloxamine.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2019 Cerner Multum, Inc. Version: 2.01. Revision date: 9/30/2019.

Your use of the content provided in this service indicates that you have read, understood and agree to the End-User License Agreement, which can be accessed by End-User License Agreement, which can be accessed by clicking on this link.

News & Events

View All

Travel Warnings and Tips for Pregnant Women

If you decide to vacation, visit old friends, or must travel for work, pregnancy shouldn’t stop you from flying or