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rolapitant

Pronunciation: roe LA pi tant

Brand: Varubi

What is the most important information I should know about rolapitant?

Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.

What is rolapitant?

Rolapitant is used together with other medicines to prevent nausea and vomiting caused by cancer chemotherapy.

Rolapitant may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before using rolapitant?

Some medicines can cause unwanted or dangerous effects when used with rolapitant. Your doctor may change your treatment plan if you also use:

  • pimozide; or
  • thioridazine.

Tell your doctor if you have ever had:

  • liver disease.

Tell your doctor if you are pregnant or breastfeeding.

This medicine may affect fertility (your ability to have children) for a short time.

Rolapitant is not approved for use by anyone younger than 18 years old.

How should I use rolapitant?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Rolapitant is usually given on Day 1 of your chemotherapy treatment.

Rolapitant is given either as a tablet taken by mouth, or as an injection infused into a vein. A healthcare provider will give the injection.

You may take rolapitant tablets with or without food.

You should not take rolapitant tablets more than once every 14 days.

You will be given other medication to prevent nausea or vomiting. Keep using these medicines for as long as your doctor has prescribed. Read the medication guide or patient instructions provided with each medication.

Store the tablets at room temperature away from moisture and heat.

What happens if I miss a dose?

Call your doctor for instructions if you forget to take the tablets at the correct time before chemotherapy. The timing of your rolapitant dose is important for this medicine to be effective.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid after using rolapitant?

For at least 1 month after you use rolapitant, avoid using any cough or cold medicine that contains dextromethorphan. Talk to your doctor about how to best treat a cough due to the common cold.

What are the possible side effects of rolapitant?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • pain or burning when you urinate;
  • low red blood cells (anemia) --pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet; or
  • low white blood cell counts --fever, swollen gums, painful mouth sores, skin sores, cold or flu symptoms, cough, trouble breathing.

Common side effects may include:

  • low blood cell counts;
  • mouth sores;
  • hiccups;
  • dizziness; or
  • loss of appetite.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect rolapitant?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Many drugs can affect rolapitant, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using. For at least 28 days after you use rolapitant, it could affect other medicines you are using.

Where can I get more information?

Your pharmacist can provide more information about rolapitant.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2019 Cerner Multum, Inc. Version: 6.01. Revision date: 4/10/2019.

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