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Atypical squamous cells (ASC) of the cervix

Atypical squamous cells (ASC) are abnormal cells found on a Pap test, but the reason for the abnormalities is not known. The causes of ASC can include infection and inflammation.

ASC is further classified as:

  • ASC of undetermined significance (ASC-US).
  • ASC but cannot exclude high-grade squamous intraepithelial lesion (HSIL) (ASC-H).

Current as of: May 1, 2026

Author: WebMD Ignite Staff

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All WebMD Ignite education is reviewed by a team that includes physicians, nurses, advanced practitioners, registered dieticians, and other healthcare professionals.

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