Our Health Library information does not replace the advice of a doctor. Please be advised that this information is made available to assist our patients to learn more about their health. Our providers may not see and/or treat all topics found herein.

HIV: Nonprogressors and HIV-Resistant People

Overview

What are HIV nonprogressors and HIV-resistant people?

A few people with HIV are described as nonprogressors. These people have HIV that does not progress to more severe symptoms or disease, but they can still spread HIV. Most nonprogressors:

  • Have lived with the infection for 10 to 15 years and remained healthy.
  • Do not have declining CD4+ cell counts.
  • Have a very low level of HIV in their blood.

A small number of people never become infected with HIV despite years of exposure to the virus. For example, they may have repeated, unprotected sex with an infected person. These people are said to be HIV-resistant. These people are never infected, so they can't spread HIV.

Studies are under way to determine why some people either don't become infected with HIV or, if they do, why they don't develop symptoms or lose CD4+ cells. Research has shown that:

  • Some people's CD4+ cells are relatively resistant to HIV. If HIV cannot attach itself to CD4+ cells, it cannot destroy them.
  • Some people's immune systems may be better able to destroy the virus.
  • Some strains of HIV may not be as harmful.

Related Information

    Credits

    Current as of: June 12, 2023

    Author: Healthwise Staff
    Clinical Review Board
    All Healthwise education is reviewed by a team that includes physicians, nurses, advanced practitioners, registered dieticians, and other healthcare professionals.

    News & Events

    View All

    How Your Lifestyle Could Be Impacting Your Fertility

    The frustrating and sad effects of a couple who has been attempting to start a family is hard to describe. One moment they want to give up,

    Facebook

    Twitter

    YouTube

    Phone

    Schedule an Appointment Online