Our Health Library information does not replace the advice of a doctor. Please be advised that this information is made available to assist our patients to learn more about their health. Our providers may not see and/or treat all topics found herein.

Prediabetes: Progression to type 2 diabetes

After 3 years, about 14 out of 100 people who made major lifestyle changes got type 2 diabetes. Compare that to about 22 out of 100 people who took metformin and about 29 out of 100 people who took a placebo pill and got type 2 diabetes. After 10 years, about 27 out of 100 people who made major lifestyle changes got type 2 diabetes. Compare that to about 42 out of 100 people who took metformin and about 52 out of 100 people who took a placebo pill and got type 2 diabetes. After 15 years, about 55 out of 100 people who made major lifestyle changes got type 2 diabetes. Compare that to about 56 out of 100 people who took metformin and about 62 out of 100 people who took a placebo pill and got type 2 diabetes.

Making major lifestyle changes or taking metformin both work better than a placebo pill at delaying or preventing type 2 diabetes. For many people, making major lifestyle changes works better than taking metformin to help delay or prevent type 2 diabetes for up to 10 years. A follow-up study at 15 years showed that making major lifestyle changes was about equal to taking metformin in helping to delay or prevent type 2 diabetes. But doing both of these things may give you the best chance of delaying or preventing type 2 diabetes over the long term.

The information shown here is based on the best available evidence.

Current as of: July 7, 2025

Author: Ignite Healthwise, LLC Staff
Clinical Review Board
All Ignite Healthwise, LLC education is reviewed by a team that includes physicians, nurses, advanced practitioners, registered dieticians, and other healthcare professionals.

Current as of: July 7, 2025

Author: Ignite Healthwise, LLC Staff

Clinical Review Board
All Ignite Healthwise, LLC education is reviewed by a team that includes physicians, nurses, advanced practitioners, registered dieticians, and other healthcare professionals.

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All deliveries will take place at Grandview Medical Center. Please plan accordingly. If you have any questions, don’t hesitate to contact our office!

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